| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKAP13-NTRK3-20-RERE | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-REOR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-REGO | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-REGR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-REAQ | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-ORRE | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-OROR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-ORGO | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-ORGR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GORE | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GOOR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GOGO | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GOGR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GRRE | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GROR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GRGO | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GRGR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-AQRE | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-AQOR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-AQGO | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-AQGR | 20 (40 μL) | 200 μL |
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| AKAP13-NTRK3-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Symbol : NTRK3
Gene Name : Neurotrophic receptor tyrosine kinase 3
Chromosome : CHR 15: 882,567,95-878,597,48
Locus : 15q25.3
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012]
Gene Symbol : AKAP13
Gene Name : A-kinase anchoring protein 13
Chromosome : CHR 15: 853,806,15-857,493,57
Locus : 15q25.3
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