| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALKBH3-ANO3-20-RERE | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-REOR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-REGO | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-REGR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-REAQ | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-ORRE | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-OROR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-ORGO | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-ORGR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GORE | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GOOR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GOGO | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GOGR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GRRE | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GROR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GRGO | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GRGR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-AQRE | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-AQOR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-AQGO | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-AQGR | 20 (40 μL) | 200 μL |
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| ALKBH3-ANO3-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Symbol : ANO3
Gene Name : Anoctamin 3
Chromosome : CHR 11: 261,891,22-266,632,88
Locus : 11p14.3-p14.2
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]
Gene Symbol : ALKBH3
Gene Name : AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase
Chromosome : CHR 11: 438,808,06-439,202,74
Locus : 11p11.2
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