ANAPC5-ADAM15 Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ANAPC5-ADAM15-20-RERE 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-REOR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-REGO 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-REGR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-OROR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GORE 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GROR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
ANAPC5-ADAM15-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

ADAM15 Summary

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

ADAM15 Details

Gene Symbol : ADAM15

Gene Name : ADAM metallopeptidase domain 15

Chromosome : CHR 1: 155,051,271-155,062,775

Locus : 1q21.3


ANAPC5 Summary

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]

ANAPC5 Details

Gene Symbol : ANAPC5

Gene Name : Anaphase promoting complex subunit 5

Chromosome : CHR 12: 121,354,208-121,308,244

Locus : 12q24.31


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