| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANAPC5-KDM2B-20-RERE | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-REOR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-REGO | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-REGR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-REAQ | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-ORRE | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-OROR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-ORGO | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-ORGR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GORE | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GOOR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GOGO | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GOGR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GRRE | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GROR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GRGO | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GRGR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-AQRE | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-AQOR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-AQGO | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-AQGR | 20 (40 μL) | 200 μL |
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| ANAPC5-KDM2B-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
Gene Symbol : ANAPC5
Gene Name : Anaphase promoting complex subunit 5
Chromosome : CHR 12: 121,354,208-121,308,244
Locus : 12q24.31
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : KDM2B
Gene Name : Lysine demethylase 2B
Chromosome : CHR 12: 121,582,267-121,402,288
Locus : 12q24.31
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