| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANK3-ACTA2-20-RERE | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-REOR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-REGO | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-REGR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-REAQ | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-ORRE | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-OROR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-ORGO | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-ORGR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GORE | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GOOR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GOGO | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GOGR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GRRE | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GROR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GRGO | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GRGR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-AQRE | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-AQOR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-AQGO | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-AQGR | 20 (40 μL) | 200 μL |
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| ANK3-ACTA2-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
Gene Symbol : ACTA2
Gene Name : Actin, alpha 2, smooth muscle, aorta
Chromosome : CHR 10: 889,913,96-889,350,73
Locus : 10q23.31
Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Symbol : ANK3
Gene Name : Ankyrin 3
Chromosome : CHR 10: 607,335,25-600,262,97
Locus : 10q21.2
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