| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANK3-CDK1-20-RERE | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-REOR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-REGO | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-REGR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-REAQ | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-ORRE | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-OROR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-ORGO | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-ORGR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GORE | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GOOR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GOGO | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GOGR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GRRE | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GROR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GRGO | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GRGR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-AQRE | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-AQOR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-AQGO | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-AQGR | 20 (40 μL) | 200 μL |
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| ANK3-CDK1-20-AQAQ | 20 (40 μL) | 200 μL |
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Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Symbol : ANK3
Gene Name : Ankyrin 3
Chromosome : CHR 10: 607,335,25-600,262,97
Locus : 10q21.2
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Gene Symbol : CDK1
Gene Name : Cyclin dependent kinase 1
Chromosome : CHR 10: 607,783,30-607,948,51
Locus : 10q21.2
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