| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANK3-SP2-20-RERE | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-REOR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-REGO | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-REGR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-REAQ | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-ORRE | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-OROR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-ORGO | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-ORGR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GORE | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GOOR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GOGO | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GOGR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GRRE | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GROR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GRGO | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GRGR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-AQRE | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-AQOR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-AQGO | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-AQGR | 20 (40 μL) | 200 μL |
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| ANK3-SP2-20-AQAQ | 20 (40 μL) | 200 μL |
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Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Symbol : ANK3
Gene Name : Ankyrin 3
Chromosome : CHR 10: 607,335,25-600,262,97
Locus : 10q21.2
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]
Gene Symbol : SP2
Gene Name : Sp2 transcription factor
Chromosome : CHR 17: 478,960,31-479,322,70
Locus : 17q21.32
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