NCALD Summary

This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

NCALD Details

Gene Symbol : NCALD

Gene Name : Neurocalcin delta

Chromosome : CHR 8: 102,124,906-101,686,541

Locus : 8q22.3

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ANKRD46 Summary

This gene encodes a protein containing multiple ankyrin repeats. Ankyrin domains function in protein-protein interactions in a variety of cellular processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

ANKRD46 Details

Gene Symbol : ANKRD46

Gene Name : Ankyrin repeat domain 46

Chromosome : CHR 8: 100,559,785-100,509,751

Locus : 8q22.3

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