RALBP1 Summary

RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010]

RALBP1 Details

Gene Symbol : RALBP1

Gene Name : RalA binding protein 1

Chromosome : CHR 18: 947,553,1-953,810,7

Locus : 18p11.22

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ANO7 Summary

This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011]

ANO7 Details

Gene Symbol : ANO7

Gene Name : Anoctamin 7

Chromosome : CHR 2: 241,188,508-241,239,601

Locus : 2q37.3

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