| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANTXR1-APLF-20-RERE | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-REOR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-REGO | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-REGR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-REAQ | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-ORRE | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-OROR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-ORGO | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-ORGR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GORE | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GOOR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GOGO | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GOGR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GRRE | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GROR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GRGO | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GRGR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-AQRE | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-AQOR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-AQGO | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-AQGR | 20 (40 μL) | 200 μL |
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| ANTXR1-APLF-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Gene Symbol : ANTXR1
Gene Name : Anthrax toxin receptor 1
Chromosome : CHR 2: 690,131,43-692,493,26
Locus : 2p13.3
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008]
Gene Symbol : APLF
Gene Name : Aprataxin and PNKP like factor
Chromosome : CHR 2: 684,675,58-685,801,61
Locus : 2p13.3
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