ANXA6-UTRN Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ANXA6-UTRN-20-RERE 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-REOR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-REGO 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-REGR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-OROR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GORE 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GROR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
ANXA6-UTRN-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

ANXA6 Summary

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]

ANXA6 Details

Gene Symbol : ANXA6

Gene Name : Annexin A6

Chromosome : CHR 5: 151,157,881-151,100,705

Locus : 5q33.1


UTRN Summary

This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

UTRN Details

Gene Symbol : UTRN

Gene Name : Utrophin

Chromosome : CHR 6: 144,284,954-144,853,033

Locus : 6q24.2


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