AOAH Summary

This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]

AOAH Details

Gene Symbol : AOAH

Gene Name : Acyloxyacyl hydrolase

Chromosome : CHR 7: 367,245,48-365,120,41

Locus : 7p14.2

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ELMO1 Summary

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

ELMO1 Details

Gene Symbol : ELMO1

Gene Name : Engulfment and cell motility 1

Chromosome : CHR 7: 374,494,08-368,529,05

Locus : 7p14.2-p14.1

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