| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP1B1-CLCN3-20-RERE | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-REOR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-REGO | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-REGR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-REAQ | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-ORRE | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-OROR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-ORGO | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-ORGR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GORE | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GOOR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GOGO | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GOGR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GRRE | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GROR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GRGO | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GRGR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-AQRE | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-AQOR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-AQGO | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-AQGR | 20 (40 μL) | 200 μL |
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| AP1B1-CLCN3-20-AQAQ | 20 (40 μL) | 200 μL |
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Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Symbol : AP1B1
Gene Name : Adaptor related protein complex 1 beta 1 subunit
Chromosome : CHR 22: 293,885,82-293,276,79
Locus : 22q12.2
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Symbol : CLCN3
Gene Name : Chloride voltage-gated channel 3
Chromosome : CHR 4: 169,620,520-169,723,186
Locus : 4q33
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