AP1B1 Summary

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

AP1B1 Details

Gene Symbol : AP1B1

Gene Name : Adaptor related protein complex 1 beta 1 subunit

Chromosome : CHR 22: 293,885,82-293,276,79

Locus : 22q12.2

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NIPSNAP1 Summary

This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

NIPSNAP1 Details

Gene Symbol : NIPSNAP1

Gene Name : Nipsnap homolog 1

Chromosome : CHR 22: 295,813,36-295,548,07

Locus : 22q12.2

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