| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AP1M1-RAB8A-20-RERE | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-REOR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-REGO | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-REGR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-REAQ | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-ORRE | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-OROR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-ORGO | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-ORGR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-ORAQ | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GORE | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GOOR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GOGO | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GOGR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GOAQ | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GRRE | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GROR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GRGO | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GRGR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-GRAQ | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-AQRE | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-AQOR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-AQGO | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-AQGR | 20 (40 μL) | 200 μL |
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| AP1M1-RAB8A-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]
Gene Symbol : RAB8A
Gene Name : RAB8A, member RAS oncogene family
Chromosome : CHR 19: 161,116,79-161,336,34
Locus : 19p13.11
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : AP1M1
Gene Name : Adaptor related protein complex 1 mu 1 subunit
Chromosome : CHR 19: 161,978,53-162,353,44
Locus : 19p13.11
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