APC Summary

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]

APC Details

Gene Symbol : APC

Gene Name : APC, WNT signaling pathway regulator

Chromosome : CHR 5: 112,707,504-112,846,238

Locus : 5q22.2

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SLC27A6 Summary

This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

SLC27A6 Details

Gene Symbol : SLC27A6

Gene Name : Solute carrier family 27 member 6

Chromosome : CHR 5: 128,965,126-129,033,641

Locus : 5q23.3

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