APP-EEA1 Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
APP-EEA1-20-RERE 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-REOR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-REGO 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-REGR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-OROR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GORE 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GROR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
APP-EEA1-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

APP Summary

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]

APP Details

Gene Symbol : APP

Gene Name : Amyloid beta precursor protein

Chromosome : CHR 21: 261,711,27-258,805,49

Locus : 21q21.3


EEA1 Details

Gene Symbol : EEA1

Gene Name : Early endosome antigen 1

Chromosome : CHR 12: 929,752,27-927,725,08

Locus : 12q22


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