| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGAP12-SVIL-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-ORGR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGAP12-SVIL-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016]
Gene Symbol : SVIL
Gene Name : Supervillin
Chromosome : CHR 10: 297,370,00-294,573,37
Locus : 10p11.23
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Symbol : ARHGAP12
Gene Name : Rho GTPase activating protein 12
Chromosome : CHR 10: 319,288,75-318,053,97
Locus : 10p11.22
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