ARHGAP5 Summary

Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ARHGAP5 Details

Gene Symbol : ARHGAP5

Gene Name : Rho GTPase activating protein 5

Chromosome : CHR 14: 320,761,51-321,597,27

Locus : 14q12

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LSAMP Summary

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

LSAMP Details

Gene Symbol : LSAMP

Gene Name : Limbic system-associated membrane protein

Chromosome : CHR 3: 116,445,541-115,802,362

Locus : 3q13.31

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