ARHGEF1 Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

ARHGEF1 Details

Gene Symbol : ARHGEF1

Gene Name : Rho guanine nucleotide exchange factor 1

Chromosome : CHR 19: 418,831,99-419,074,53

Locus : 19q13.2

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UCKL1 Summary

The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

UCKL1 Details

Gene Symbol : UCKL1

Gene Name : Uridine-cytidine kinase 1 like 1

Chromosome : CHR 20: 639,594,34-639,398,28

Locus : 20q13.33

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