| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARHGEF10L-PAK4-20-RERE | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-REOR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-REGR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-REAQ | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-ORRE | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-OROR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-ORGO | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-ORGR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GOOR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GOGO | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GROR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GRGR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-AQRE | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-AQGO | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-AQGR | 20 (40 μL) | 200 μL |
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| ARHGEF10L-PAK4-20-AQAQ | 20 (40 μL) | 200 μL |
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PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : PAK4
Gene Name : P21 (RAC1) activated kinase 4
Chromosome : CHR 19: 391,257,79-391,794,05
Locus : 19q13.2
This gene belongs to the RhoGEF subfamily of RhoGTPases. Members of this subfamily are activated by specific guanine nucleotide exchange factors (GEFs) and are involved in signal transduction. The encoded protein shows cytosolic distribution. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2016]
Gene Symbol : ARHGEF10L
Gene Name : Rho guanine nucleotide exchange factor 10 like
Chromosome : CHR 1: 175,201,96-176,978,74
Locus : 1p36.13
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