ALDH9A1 Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]

ALDH9A1 Details

Gene Symbol : ALDH9A1

Gene Name : Aldehyde dehydrogenase 9 family member A1

Chromosome : CHR 1: 165,698,662-165,662,211

Locus : 1q24.1

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ARHGEF11 Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

ARHGEF11 Details

Gene Symbol : ARHGEF11

Gene Name : Rho guanine nucleotide exchange factor 11

Chromosome : CHR 1: 157,046,902-156,934,839

Locus : 1q23.1

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