TECR Summary

This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2011]

TECR Details

Gene Symbol : TECR

Gene Name : Trans-2,3-enoyl-CoA reductase

Chromosome : CHR 19: 145,277,59-145,659,79

Locus : 19p13.12

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ARHGEF18 Summary

Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

ARHGEF18 Details

Gene Symbol : ARHGEF18

Gene Name : Rho/Rac guanine nucleotide exchange factor 18

Chromosome : CHR 19: 734,890,0-747,698,9

Locus : 19p13.2

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