ARHGEF3-LTF Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ARHGEF3-LTF-20-RERE 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-REOR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-REGO 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-REGR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-OROR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GORE 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GROR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
ARHGEF3-LTF-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

LTF Summary

This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

LTF Details

Gene Symbol : LTF

Gene Name : Lactotransferrin

Chromosome : CHR 3: 464,852,33-464,360,04

Locus : 3p21.31


ARHGEF3 Summary

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ARHGEF3 Details

Gene Symbol : ARHGEF3

Gene Name : Rho guanine nucleotide exchange factor 3

Chromosome : CHR 3: 570,793,07-567,274,17

Locus : 3p14.3


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