TIAM2 Summary

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

TIAM2 Details

Gene Symbol : TIAM2

Gene Name : T-cell lymphoma invasion and metastasis 2

Chromosome : CHR 6: 155,090,288-155,257,722

Locus : 6q25.2-q25.3

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ARID1B Summary

This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

ARID1B Details

Gene Symbol : ARID1B

Gene Name : AT-rich interaction domain 1B

Chromosome : CHR 6: 156,777,846-157,210,778

Locus : 6q25.3

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