ARID3A Summary

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

ARID3A Details

Gene Symbol : ARID3A

Gene Name : AT-rich interaction domain 3A

Chromosome : CHR 19: 925,732-975,933

Locus : 19p13.3

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MORC2 Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

MORC2 Details

Gene Symbol : MORC2

Gene Name : MORC family CW-type zinc finger 2

Chromosome : CHR 22: 309,684,96-309,251,29

Locus : 22q12.2

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