| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARNTL2-ITPR2-20-RERE | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-REOR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-REGO | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-REGR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-REAQ | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-ORRE | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-OROR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-ORGO | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-ORGR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GORE | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GOOR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GOGO | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GOGR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GRRE | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GROR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GRGO | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GRGR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-AQRE | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-AQOR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-AQGO | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-AQGR | 20 (40 μL) | 200 μL |
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| ARNTL2-ITPR2-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the inositol 1,4,5-triphosphate receptor family, whose members are second messenger intracellular calcium release channels. These proteins mediate a rise in cytoplasmic calcium in response to receptor activated production of inositol triphosphate. Inositol triphosphate receptor-mediated signaling is involved in many processes including cell migration, cell division, smooth muscle contraction, and neuronal signaling. This protein is a type 2 receptor that consists of a cytoplasmic amino-terminus that binds inositol triphosphate, six membrane-spanning helices that contribute to the ion pore, and a short cytoplasmic carboxy-terminus. A mutation in this gene has been associated with anhidrosis, suggesting that intracellular calcium release mediated by this protein is required for eccrine sweat production. [provided by RefSeq, Apr 2015]
Gene Symbol : ITPR2
Gene Name : Inositol 1,4,5-trisphosphate receptor type 2
Chromosome : CHR 12: 268,331,97-263,353,36
Locus : 12p11.23
This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Symbol : ARNTL2
Gene Name : Aryl hydrocarbon receptor nuclear translocator like 2
Chromosome : CHR 12: 273,328,53-274,258,12
Locus : 12p11.23
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