SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ARRB1-PRCP-20-RERE | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-REOR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-REAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-ORRE | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-OROR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-ORGO | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-ORAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GORE | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GOOR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GOGO | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GOAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GRGR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-GRAQ | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-AQRE | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-AQGO | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-AQGR | 20 (40 μL) | 200 μL | Request Pricing | |
ARRB1-PRCP-20-AQAQ | 20 (40 μL) | 200 μL | Request Pricing |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Gene Symbol : ARRB1
Gene Name : Arrestin beta 1
Chromosome : CHR 11: 753,518,30-752,601,21
Locus : 11q13.4
This gene encodes a member of the peptidase S28 family of serine exopeptidases. The encoded preproprotein is proteolytically processed to generate the mature lysosomal prolylcarboxypeptidase. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. A pseudogene of this gene has been identified on chromosome 2. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Symbol : PRCP
Gene Name : Prolylcarboxypeptidase
Chromosome : CHR 11: 829,017,39-828,229,39
Locus : 11q14.1
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