| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AS3MT-HERC4-20-RERE | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-REOR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-REGO | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-REGR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-REAQ | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-ORRE | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-OROR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-ORGO | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-ORGR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-ORAQ | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GORE | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GOOR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GOGO | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GOGR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GOAQ | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GRRE | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GROR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GRGO | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GRGR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-GRAQ | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-AQRE | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-AQOR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-AQGO | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-AQGR | 20 (40 μL) | 200 μL |
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| AS3MT-HERC4-20-AQAQ | 20 (40 μL) | 200 μL |
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HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]
Gene Symbol : HERC4
Gene Name : HECT and RLD domain containing E3 ubiquitin protein ligase 4
Chromosome : CHR 10: 680,753,47-679,218,98
Locus : 10q21.3
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism (Lin et al., 2002 [PubMed 11790780]).[supplied by OMIM, Mar 2008]
Gene Symbol : AS3MT
Gene Name : Arsenite methyltransferase
Chromosome : CHR 10: 102,869,452-102,901,898
Locus : 10q24.32
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