ASAP1 Summary

This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

ASAP1 Details

Gene Symbol : ASAP1

Gene Name : ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Chromosome : CHR 8: 130,443,847-130,052,103

Locus : 8q24.21-q24.22

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LRRCC1 Summary

This gene encodes a centrosomal protein that maintains the structural integrity of the centrosome and plays a key role in mitotic spindle formation. The encoded protein contains an N-terminal leucine-rich repeat domain and a C-terminal coiled-coil domain. It associates with the centrosome throughout the cell cycle and accumulates on the mitotic centrosome. [provided by RefSeq, Mar 2017]

LRRCC1 Details

Gene Symbol : LRRCC1

Gene Name : Leucine rich repeat and coiled-coil centrosomal protein 1

Chromosome : CHR 8: 851,070,87-851,460,79

Locus : 8q21.2

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