HSPH1 Summary

This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017]

HSPH1 Details

Gene Symbol : HSPH1

Gene Name : Heat shock protein family H (Hsp110) member 1

Chromosome : CHR 13: 311,631,08-311,349,73

Locus : 13q12.3

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ASXL2 Summary

This gene encodes a member of a family of epigenetic regulators that bind various histone-modifying enzymes and are involved in the assembly of transcription factors at specific genomic loci. Naturally occurring mutations in this gene are associated with cancer in several tissue types (breast, bladder, pancreas, ovary, prostate, and blood). This gene plays an important role in neurodevelopment, cardiac function, adipogenesis, and osteoclastogenesis. [provided by RefSeq, Feb 2017]

ASXL2 Details

Gene Symbol : ASXL2

Gene Name : Additional sex combs like 2, transcriptional regulator

Chromosome : CHR 2: 258,784,84-257,337,57

Locus : 2p23.3

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