MAP3K13 Summary

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]

MAP3K13 Details

Gene Symbol : MAP3K13

Gene Name : Mitogen-activated protein kinase kinase kinase 13

Chromosome : CHR 3: 185,282,937-185,489,093

Locus : 3q27.2

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ATP11B Summary

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]

ATP11B Details

Gene Symbol : ATP11B

Gene Name : ATPase phospholipid transporting 11B (putative)

Chromosome : CHR 3: 182,793,502-182,923,009

Locus : 3q26.33

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