ATP11B Summary

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]

ATP11B Details

Gene Symbol : ATP11B

Gene Name : ATPase phospholipid transporting 11B (putative)

Chromosome : CHR 3: 182,793,502-182,923,009

Locus : 3q26.33

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MED10 Summary

MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

MED10 Details

Gene Symbol : MED10

Gene Name : Mediator complex subunit 10

Chromosome : CHR 5: 637,852,5-637,192,5

Locus : 5p15.31

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