NET1 Summary

This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

NET1 Details

Gene Symbol : NET1

Gene Name : Neuroepithelial cell transforming 1

Chromosome : CHR 10: 541,255,0-545,905,5

Locus : 10p15.1

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ATP11B Summary

P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM, Feb 2005]

ATP11B Details

Gene Symbol : ATP11B

Gene Name : ATPase phospholipid transporting 11B (putative)

Chromosome : CHR 3: 182,793,502-182,923,009

Locus : 3q26.33

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