ATP1B1 Summary

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]

ATP1B1 Details

Gene Symbol : ATP1B1

Gene Name : ATPase Na+/K+ transporting subunit beta 1

Chromosome : CHR 1: 169,106,708-169,132,721

Locus : 1q24.2

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THSD4 Details

Gene Symbol : THSD4

Gene Name : Thrombospondin type 1 domain containing 4

Chromosome : CHR 15: 711,156,15-717,833,82

Locus : 15q23

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