ATP1B3-RNF7 Fusion FISH Probe


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ATP1B3-RNF7-20-RERE 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-REOR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-REGO 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-REGR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-REAQ 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-ORRE 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-OROR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-ORGO 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-ORAQ 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GORE 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GOOR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GOGO 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GOAQ 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GROR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GRGR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-GRAQ 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-AQRE 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-AQOR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-AQGO 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-AQGR 20 (40 μL) 200 μL color color Request Pricing
ATP1B3-RNF7-20-AQAQ 20 (40 μL) 200 μL color color Request Pricing

ATP1B3 Summary

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]

ATP1B3 Details

Gene Symbol : ATP1B3

Gene Name : ATPase Na+/K+ transporting subunit beta 3

Chromosome : CHR 3: 141,876,627-141,926,539

Locus : 3q23


RNF7 Summary

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

RNF7 Details

Gene Symbol : RNF7

Gene Name : Ring finger protein 7

Chromosome : CHR 3: 141,738,208-141,746,802

Locus : 3q23


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