| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP2B1-CEP290-20-RERE | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-REOR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-REGO | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-REGR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-OROR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-ORGR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GORE | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GROR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP2B1-CEP290-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : ATP2B1
Gene Name : ATPase plasma membrane Ca2+ transporting 1
Chromosome : CHR 12: 897,093,52-895,880,48
Locus : 12q21.33
This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008]
Gene Symbol : CEP290
Gene Name : Centrosomal protein 290
Chromosome : CHR 12: 881,422,15-880,490,12
Locus : 12q21.32
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