| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP2B1-EXOC4-20-RERE | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-REOR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-REGO | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-REGR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-OROR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-ORGR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GORE | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GROR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP2B1-EXOC4-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : ATP2B1
Gene Name : ATPase plasma membrane Ca2+ transporting 1
Chromosome : CHR 12: 897,093,52-895,880,48
Locus : 12q21.33
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : EXOC4
Gene Name : Exocyst complex component 4
Chromosome : CHR 7: 133,253,066-134,067,136
Locus : 7q33
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