| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP2B4-NFASC-20-RERE | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-REOR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-REGO | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-REGR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-OROR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-ORGR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GORE | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GROR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP2B4-NFASC-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : ATP2B4
Gene Name : ATPase plasma membrane Ca2+ transporting 4
Chromosome : CHR 1: 203,626,786-203,744,080
Locus : 1q32.1
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
Gene Symbol : NFASC
Gene Name : Neurofascin
Chromosome : CHR 1: 204,828,651-205,022,821
Locus : 1q32.1
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