| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATP2B4-OPTC-20-RERE | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-REOR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-REGO | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-REGR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-REAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-ORRE | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-OROR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-ORGO | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-ORGR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GORE | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GOOR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GOGO | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GROR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GRGR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-AQRE | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-AQGO | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-AQGR | 20 (40 μL) | 200 μL |
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| ATP2B4-OPTC-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : ATP2B4
Gene Name : ATPase plasma membrane Ca2+ transporting 4
Chromosome : CHR 1: 203,626,786-203,744,080
Locus : 1q32.1
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008]
Gene Symbol : OPTC
Gene Name : Opticin
Chromosome : CHR 1: 203,494,142-203,508,948
Locus : 1q32.1
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