| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATRX-ABCB7-20-RERE | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-REOR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-REGO | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-REGR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-REAQ | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-ORRE | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-OROR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-ORGO | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-ORGR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-ORAQ | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GORE | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GOOR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GOGO | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GOGR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GOAQ | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GRRE | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GROR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GRGO | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GRGR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-GRAQ | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-AQRE | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-AQOR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-AQGO | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-AQGR | 20 (40 μL) | 200 μL |
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| ATRX-ABCB7-20-AQAQ | 20 (40 μL) | 200 μL |
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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Gene Symbol : ABCB7
Gene Name : ATP binding cassette subfamily B member 7
Chromosome : CHR X: 751,563,39-750,531,71
Locus : Xq13.3
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017]
Gene Symbol : ATRX
Gene Name : ATRX, chromatin remodeler
Chromosome : CHR X: 777,862,68-775,048,77
Locus : Xq21.1
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